Description

3-Pyridinol, 2-Amino-5-Chloro-4-Fluoro- is a high-purity, multi-substituted pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and aminated structure makes it an invaluable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antibacterial research.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand & Catalyst Development: Used to create specialized ligands for metal catalysis and asymmetric synthesis.
• Material Science Research: Intermediate for synthesizing functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes and diagnostic agents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules.

Basic Information

Product Name	3-Pyridinol, 2-Amino-5-Chloro-4-Fluoro-
CAS No.	1003710-83-5
Molecular Formula	C5H4ClFN2O
Molecular Weight	162.55 g/mol
Synonyms	2-Amino-5-chloro-4-fluoro-3-pyridinol; 5-Chloro-4-fluoro-2-amino-3-pyridinol; 2-Amino-5-chloro-4-fluoropyridin-3-ol; 3-Hydroxy-2-amino-5-chloro-4-fluoropyridine; 2-Amino-5-chloro-4-fluoro-3-hydroxypyridine; 5-Chloro-4-fluoro-3-hydroxy-2-aminopyridine; ACFP Intermediate
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Chloro-4-Fluoro-3-Pyridinol is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, typically determined by HPLC, NMR, and MS. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and cGMP intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.