Description

2-Amino-5-Bromo-4-Fluoro-3-Hydroxypyridine CAS NO 1003710-78-8 is a high-purity, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and functionalized structure makes it an indispensable intermediate for creating complex molecules with targeted biological and material properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Building block for synthesizing advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology & Proteomics: Utilized in the design of molecular probes, tags, and linkers for studying biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Item	Details
Product Name	2-Amino-5-Bromo-4-Fluoro-3-Hydroxypyridine
CAS No.	1003710-78-8
Molecular Formula	C5H4BrFN2O
Molecular Weight	206.99 g/mol
Synonyms	5-Bromo-4-fluoro-3-hydroxy-2-aminopyridine; 2-Amino-5-bromo-4-fluoro-3-pyridinol; 3-Hydroxy-2-amino-5-bromo-4-fluoropyridine; 5-Bromo-4-fluoro-2-amino-3-pyridinol; 2-Amino-3-hydroxy-5-bromo-4-fluoropyridine; 4-Fluoro-5-bromo-2-amino-3-hydroxypyridine; 1003710-78-8
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Bromo-4-Fluoro-3-Hydroxypyridine is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.