Description

2-Amino-4-Bromo-5-Chloro-3-Hydroxypyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and pesticides with enhanced efficacy.
• Ligand and Catalyst Development: Used to create specialized ligands for metal catalysis and coordination chemistry.
• Material Science Research: Intermediate for synthesizing functional organic materials and dyes.
• Academic & R&D Laboratories: Serves as a versatile starting material for methodological studies and novel heterocycle construction.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions where required.

Basic Information

Product Name	2-Amino-4-Bromo-5-Chloro-3-Hydroxypyridine
CAS No.	1003710-53-9
Molecular Formula	C5H4BrClN2O
Molecular Weight	223.46 g/mol
Synonyms	5-Chloro-4-bromo-3-hydroxy-2-pyridinamine; 3-Hydroxy-2-amino-4-bromo-5-chloropyridine; 4-Bromo-5-chloro-3-hydroxy-2-aminopyridine; 2-Amino-4-bromo-5-chloro-3-pyridinol; ABCHP; 2-Pyridinamine, 4-bromo-5-chloro-3-hydroxy-; 1003710-53-9
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Bromo-5-Chloro-3-Hydroxypyridine is manufactured under strict quality management systems. We provide material with standard purity grades suitable for research and commercial synthesis, supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch. Specifications can be tailored to meet specific project requirements, including higher purity grades for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.