Description

2-Amino-3-Chloro-5-(Trifluoromethoxy)Benzoic Acid Methyl Ester is a high-value, multi-functional aromatic building block designed for advanced chemical synthesis. Its molecular structure, featuring amino, chloro, and trifluoromethoxy substituents, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients. We supply this material with a focus on consistent purity and reliable global availability to support your most demanding projects.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and functional handles for further modification.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling reagent in the development of chemical probes and enzyme inhibitors for biological pathway analysis.
• Custom Synthesis & Contract Manufacturing: A versatile starting material for custom chemical synthesis services, enabling the production of complex, fluorinated target molecules.

Basic Information

Product Name	2-Amino-3-Chloro-5-(Trifluoromethoxy)Benzoic Acid Methyl Ester
CAS No.	1003708-08-4
Molecular Formula	C9H7ClF3NO3
Molecular Weight	269.60 g/mol
Synonyms	Methyl 2-Amino-3-Chloro-5-(Trifluoromethoxy)benzoate; Benzoic acid, 2-amino-3-chloro-5-(trifluoromethoxy)-, methyl ester; 2-Amino-3-chloro-5-(trifluoromethoxy)methyl benzoate; Methyl 2-amino-3-chloro-α,α,α-trifluoro-p-anisate; 1003708-08-4
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Chloro-5-(Trifluoromethoxy)Benzoic Acid Methyl Ester is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS, to ensure compliance with industry standards and your specific research or production requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.