Description

Ccr1 Antagonist CAS NO 1003566-93-5 is a potent and selective small molecule inhibitor targeting the C-C chemokine receptor type 1 (CCR1). This compound is of significant value for its role in modulating inflammatory pathways, making it a critical tool for research and development in immunology and autoimmune diseases. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies engaged in the discovery of novel therapeutics for conditions like rheumatoid arthritis, multiple sclerosis, and other inflammatory disorders.

Application

• Pharmaceutical Research & Development: A key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel anti-inflammatory and autoimmune disease therapeutics.
• Biochemical Assay Development: Used as a selective pharmacological tool to study CCR1 receptor function, signaling pathways, and ligand-receptor interactions in vitro.
• Preclinical Studies: Employed in animal models to investigate the efficacy, pharmacokinetics, and pharmacodynamics of CCR1-targeted drug candidates.
• Mechanism of Action (MoA) Studies: Essential for validating the role of the CCR1 pathway in specific disease models and for identifying potential drug combinations.
• High-Throughput Screening (HTS): Serves as a control compound in screening campaigns to discover new CCR1 antagonists or to assess off-target effects.

Basic Information

Product Name	Ccr1 Antagonist
CAS No.	1003566-93-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CCR1 Antagonist; CCR1 inhibitor; Chemokine Receptor CCR1 Antagonist; (Compound code associated with CAS 1003566-93-5); 1-[(2,4-Dichlorophenyl)methyl]-5-[[(3S)-3-[[(1R)-1-(3,4-difluorophenyl)ethyl]amino]-1-pyrrolidinyl]carbonyl]-1H-indole-3-carbonitrile (IUPAC name based on common structure); Potential research code names (e.g., BX 471 analog).
EINECS	Contact for details

Quality Control

Our Ccr1 Antagonist is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or desiccated conditions upon opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.