Description

2-Chloro-6-Isopropylpyridine-3-Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters for its role as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl and heterobiaryl structures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a building block for organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand & Catalyst Development: Employed in the preparation of specialized pyridine-based ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation in drug discovery.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-6-Isopropylpyridine-3-Boronic Acid
CAS No.	1003043-37-5
Molecular Formula	C8H11BClNO2
Molecular Weight	199.44 g/mol
Synonyms	(2-Chloro-6-(propan-2-yl)pyridin-3-yl)boronic acid; 2-Chloro-6-isopropyl-3-pyridineboronic acid; 3-Borono-2-chloro-6-isopropylpyridine; 2-Chloro-6-(1-methylethyl)-3-pyridineboronic acid; Boronic acid, B-[2-chloro-6-(1-methylethyl)-3-pyridinyl]-; 2-Chloro-6-isopropylpyridine-3-boronic acid pinacol ester (protected form)
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Isopropylpyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.