Description

2-Piperidinone, 5-Amino-, Hydrochloride (1:2), (5S)- is a high-purity, stereochemically defined chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules where the specific (S)-configuration at the 5-position is required for biological activity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the study and development of new chiral catalysts.
• Chemical Biology & Proteomics: Employed as a building block for creating specialized probes and molecular tools.
• Academic & Industrial R&D: Fundamental material for synthetic organic chemistry research and process development.
• Custom Synthesis: Starting point for contract manufacturing organizations (CMOs) producing bespoke fine chemicals for clients.

Basic Information

Product Name	2-Piperidinone, 5-Amino-, Hydrochloride (1:2), (5S)-
CAS No.	1003021-05-3
Molecular Formula	C5H10N2O • 2HCl
Molecular Weight	215.07 g/mol
Synonyms	(5S)-5-Amino-2-piperidinone dihydrochloride; (S)-5-Amino-2-piperidinone hydrochloride; 5-Amino-2-piperidinone, (S)-, hydrochloride (1:2); L-5-Amino-2-piperidinone dihydrochloride; (S)-5-Aminopiperidin-2-one dihydrochloride; 2-Piperidinone, 5-amino-, hydrochloride (1:2), (5S)-; 1003021-05-3; (S)-Amino-δ-valerolactam dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Piperidinone, 5-Amino-, Hydrochloride (1:2), (5S)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.