Description

2(1H)-Pyridinone, 1-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling the Suzuki-Miyaura cross-coupling reaction, a powerful and widely used method for forming carbon-carbon bonds under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for complex molecule synthesis.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed coupling reactions.
• Material Science Research: Enables the construction of complex organic frameworks, polymers, and liquid crystals for electronic and optical applications.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester coupling partner for introducing the substituted pyridinone moiety into target molecules.
• Chemical Library Development: Utilized in high-throughput and combinatorial chemistry for creating diverse compound libraries for screening.
• Ligand and Catalyst Synthesis: A precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name	2(1H)-Pyridinone, 1-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1002309-52-5
Molecular Formula	C12H18BNO3
Molecular Weight	235.09 g/mol
Synonyms	1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one; 1-Methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-dihydropyridin-2-one; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methylpyridin-2(1H)-one; 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-pyridinone; 1-Methyl-5-(pinacolatoboryl)pyridin-2(1H)-one; 5-Pinacolatoboryl-1-methyl-2-pyridone
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyridinone, 1-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports applications in GMP-compliant pharmaceutical development and other high-precision industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.