Description

4,5-Dimethylpyridine-3-Boronic Acid is a high-purity boronic acid derivative, a key building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific heterocyclic structures for enhanced activity.
• Material Science & Ligand Design: Serves as a building block for metal-organic frameworks (MOFs), catalysts, and specialized ligands used in homogeneous catalysis.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a versatile boronic acid coupling partner for introducing the 4,5-dimethylpyridin-3-yl moiety into target molecules.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on heterocyclic chemistry and new synthetic methodologies.

Basic Information

Product Name	4,5-Dimethylpyridine-3-Boronic Acid
CAS No.	1001907-71-6
Molecular Formula	C7H10BNO2
Molecular Weight	150.97 g/mol
Synonyms	(4,5-Dimethylpyridin-3-yl)boronic acid; 3-Borono-4,5-dimethylpyridine; 4,5-Dimethyl-3-pyridineboronic acid; 4,5-Dimethylpyridine-3-boronic acid pinacol ester (protected form); 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4,5-dimethylpyridine; 4,5-Dimethyl-3-pyridylboronic acid; B-(4,5-Dimethyl-3-pyridinyl)boronic acid
EINECS	Contact for details

Quality Control

Our 4,5-Dimethylpyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.