Description

4-Amino-6-Chloronicotinaldehyde is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and an aldehyde group on the chlorinated pyridine ring, makes it an essential intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts.
• Material Science Research: Building block for synthesizing functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for biochemical research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and libraries.

Basic Information

Product Name	4-Amino-6-Chloronicotinaldehyde
CAS No.	1001756-21-3
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	6-Chloro-4-aminonicotinaldehyde; 4-Amino-6-chloropyridine-3-carboxaldehyde; 3-Pyridinecarboxaldehyde, 4-amino-6-chloro-; 6-Chloro-4-pyridinamine-3-carboxaldehyde; 4-Amino-6-chloro-3-formylpyridine; 4-Amino-6-chloro-3-pyridinecarboxaldehyde; 4-Amino-6-chloro-3-pyridyl aldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-6-Chloronicotinaldehyde is manufactured and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle under an inert atmosphere and store under desiccant for long-term preservation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.