Description

4-Bromo-2-(Chloromethyl)Pyridine is a versatile and highly functionalized heterocyclic building block, essential for advanced organic synthesis. Its core value lies in the dual reactivity of the bromo and chloromethyl substituents, enabling precise molecular construction and derivatization. This compound is critically needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing active ingredients and novel functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for creating novel pesticides, herbicides, and fungicides with enhanced efficacy.
• Ligand and Catalyst Development: Used to construct complex pyridine-based ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems and drug discovery.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Product Name	4-Bromo-2-(Chloromethyl)Pyridine
CAS No.	1001463-32-6
Molecular Formula	C6H5BrClN
Molecular Weight	206.47 g/mol
Synonyms	2-(Chloromethyl)-4-bromopyridine; 4-Bromo-2-pyridinylmethyl chloride; 4-Bromo-2-chloromethylpyridine; Pyridine, 4-bromo-2-(chloromethyl)-; 4-Bromo-2-(chloromethyl)pyridine; (4-Bromo-2-pyridyl)methyl chloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Chloromethyl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.