Description

4-Bromo-2-(Chloromethyl)Pyridine Hydrochloride is a versatile and high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites—the bromine and chloromethyl groups—which enable selective functionalization for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially kinase inhibitors and other targeted therapeutics.
• Agrochemical Synthesis: Used to construct pyridine-based herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	4-Bromo-2-(Chloromethyl)Pyridine Hydrochloride
CAS No.	1001414-94-3
Molecular Formula	C6H6BrCl2N
Molecular Weight	242.93 g/mol
Synonyms	2-(Chloromethyl)-4-bromopyridine hydrochloride; 4-Bromo-2-(chloromethyl)pyridine HCl; 4-Bromo-2-chloromethylpyridine hydrochloride; Pyridine, 4-bromo-2-(chloromethyl)-, hydrochloride; 4-Bromo-2-(chloromethyl)pyridinium chloride
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-(Chloromethyl)Pyridine Hydrochloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality management and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.