Description

1H-Pyrrolo[2,3-B]Pyridine, 5-Fluoro-3-Iodo-1-(Phenylsulfonyl)- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which incorporates halogen and sulfonyl functional groups, enabling precise structural modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic core.
• Material Science: Serves as a building block for creating specialized organic electronic materials and functional polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring complex, halogenated pyrrolopyridine derivatives.
• Academic & Institutional Research: Used in university and R&D laboratory settings for methodological studies and novel reaction development.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 5-Fluoro-3-Iodo-1-(Phenylsulfonyl)-
CAS No.	1001413-99-5
Molecular Formula	C13H8FINO2S
Molecular Weight	387.17 g/mol
Synonyms	5-Fluoro-3-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Phenylsulfonyl)-5-fluoro-3-iodo-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-3-iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridine (common); 1H-Pyrrolo[2,3-b]pyridine, 5-fluoro-3-iodo-1-(phenylsulfonyl)-; 1001413-99-5; 5-Fluoro-3-iodo-1H-pyrrolo[2,3-b]pyridine 1-sulfonate; Fluorinated Iodopyrrolopyridine Sulfonamide
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrrolo[2,3-B]Pyridine, 5-Fluoro-3-Iodo-1-(Phenylsulfonyl)- is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.