Description

3-Pyridinecarboxamide, 1-[(3,4-Difluorophenyl)Methyl]-1,2-Dihydro-2-Oxo-n-(2-Thienylmethyl)- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development programs targeting new therapeutic agents, particularly in central nervous system (CNS) and metabolic disease areas. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary drug candidates and novel chemical entities (NCEs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• CNS-Active Compound Synthesis: Serves as a precursor for molecules targeting neurological and psychiatric disorders.
• Kinase Inhibitor Development: Potential scaffold in the development of selective kinase inhibitors for oncology and inflammatory diseases.
• Custom Synthesis Projects: Supplied to fine chemical companies for custom manufacturing and scale-up services.
• Academic Research: Utilized in university and institutional labs for biochemical and pharmacological studies.

Basic Information

Product Name	3-Pyridinecarboxamide, 1-[(3,4-Difluorophenyl)Methyl]-1,2-Dihydro-2-Oxo-n-(2-Thienylmethyl)-
CAS No.	1001413-87-1
Molecular Formula	C18H14F2N2O2S
Molecular Weight	360.38 g/mol
Synonyms	1-[(3,4-Difluorophenyl)methyl]-N-(thiophen-2-ylmethyl)-2-oxo-1,2-dihydropyridine-3-carboxamide; 1-[(3,4-Difluorobenzyl)]-N-[(2-thienyl)methyl]-2-oxo-1,2-dihydro-3-pyridinecarboxamide; 1-(3,4-Difluorobenzyl)-N-(thiophen-2-ylmethyl)-2-oxo-1,2-dihydropyridine-3-carboxamide; 1001413-87-1; AI3-53195; ZINC000103459511; SCHEMBL2180557; BDBM50389357
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), suitable for advanced research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality system is designed to support cGMP and ISO guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere if opened. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.