Description

Ethyl 1-(3,4-Difluorobenzyl)-2-Oxo-1,2-Dihydropyridine-3-Carboxylate is a high-value, synthetically derived organic compound featuring a difluorobenzyl-substituted dihydropyridone core. This molecule serves as a critical pharmaceutical intermediate and advanced building block in medicinal chemistry research and development. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its fused heterocyclic structure and fluorine substituents.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the dihydropyridone moiety.
• Chemical Biology Probes: Utilized in the development of chemical probes and tool compounds for investigating biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Ethyl 1-(3,4-Difluorobenzyl)-2-Oxo-1,2-Dihydropyridine-3-Carboxylate
CAS No.	1001412-63-0
Molecular Formula	C15H13F2NO3
Molecular Weight	293.27 g/mol
Synonyms	Ethyl 1-[(3,4-difluorophenyl)methyl]-2-oxo-1,2-dihydro-3-pyridinecarboxylate; 1-(3,4-Difluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylic Acid Ethyl Ester; 3-Pyridinecarboxylic acid, 1-[(3,4-difluorophenyl)methyl]-1,2-dihydro-2-oxo-, ethyl ester; 1,2-Dihydropyridin-2-one derivative; DHP Intermediate CAS 1001412-63-0
EINECS	Contact for details

Quality Control

Our Ethyl 1-(3,4-Difluorobenzyl)-2-Oxo-1,2-Dihydropyridine-3-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development from research to commercial scale with appropriate quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.