Description

1H-Pyrrolo[2,3-B]Pyridine-3-Sulfonyl Chloride CAS NO 1001412-59-4 is a high-purity, heterocyclic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its reactive sulfonyl chloride group, which enables efficient introduction of the sulfonamide moiety into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Building block for creating functional polymers, dyes, and advanced organic materials with specific electronic or photophysical properties.
• Chemical Biology: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and activity-based protein profiling reagents.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Sulfonyl Chloride
CAS No.	1001412-59-4
Molecular Formula	C7H5ClN2O2S
Molecular Weight	216.65 g/mol
Synonyms	7-Azaindole-3-sulfonyl chloride; 1H-Pyrrolo[2,3-b]pyridine-3-sulfonyl chloride; 3-(Chlorosulfonyl)-1H-pyrrolo[2,3-b]pyridine; 7-Aza-1H-indole-3-sulfonyl chloride; 1H-7-Azaindole-3-sulfonyl chloride; 3-Chlorosulfonyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-3-sulfonchlorid
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.