Description

Ethyl n-Boc-2,4,4-Trimethyl-5-Oxopyrrolidine-2-Carboxylate is a high-purity, protected pyrrolidine derivative, a crucial building block in modern organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Synthesis: Serves as a constrained proline analogue for constructing novel peptide-like molecules with enhanced stability and biological activity.
• Agrochemical Research: Used as a precursor in the development of advanced herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis Ligand Precursor: Provides a chiral backbone for the development of novel ligands used in asymmetric hydrogenation and other catalytic transformations.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for client-specific custom synthesis projects.

Basic Information

Product Name	Ethyl n-Boc-2,4,4-Trimethyl-5-Oxopyrrolidine-2-Carboxylate
CAS No.	1001353-88-3
Molecular Formula	C15H25NO5
Molecular Weight	299.36 g/mol
Synonyms	Ethyl 1-(tert-Butoxycarbonyl)-2,4,4-trimethyl-5-oxopyrrolidine-2-carboxylate; 1-Boc-2,4,4-Trimethyl-5-oxopyrrolidine-2-carboxylic Acid Ethyl Ester; 2,4,4-Trimethyl-5-oxo-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester 2-Ethyl Ester; 1-N-Boc-2,4,4-trimethyl-5-oxopyrrolidine-2-carboxylic acid ethyl ester; Ethyl 1-Boc-2,4,4-trimethyl-5-oxo-2-pyrrolidinecarboxylate; 2-Carbethoxy-1-Boc-2,4,4-trimethyl-5-pyrrolidinone
EINECS	Contact for details

Quality Control

Our Ethyl n-Boc-2,4,4-Trimethyl-5-Oxopyrrolidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.