Description

2-Borono-1H-Indol-1-Carboxylic Acid 1-Methyl Ester is a high-value, synthetically versatile boronic ester derivative of indole, serving as a critical building block in modern organic synthesis. Its primary value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed as a tool compound or linker in the development of biochemical probes and affinity purification reagents.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and catalysis research within university and CRO laboratories.
• Custom Synthesis: Used by fine chemical manufacturers for the bespoke production of complex, boronic acid-containing molecules for client projects.

Basic Information

Product Name	2-Borono-1H-Indol-1-Carboxylic Acid 1-Methyl Ester
CAS No.	1001162-89-5
Molecular Formula	C10H10BNO4
Molecular Weight	219.00 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 2-borono-, 1-methyl ester; 2-Boronindole-1-carboxylic Acid Methyl Ester; Methyl 2-borono-1H-indole-1-carboxylate; 2-Bpin-1H-Indole-1-Carboxylic Acid Methyl Ester (common abbreviation); 1-Methyl 2-boronindole-1-carboxylate; (1-Methoxycarbonyl-1H-indol-2-yl)boronic acid; B-2-Indolylboronic acid 1-methyl ester
EINECS	Contact for details

Quality Control

Our 2-Borono-1H-Indol-1-Carboxylic Acid 1-Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically ≥95% (by HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, and custom synthesis and purification to meet specific client specifications (e.g., >98%, >99%) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and easily oxidized nature. Allow the sealed container to reach room temperature before opening to prevent condensation and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.