Description

4-[5-(4-Fluorobenzyl)-1H-Pyrazol-3-Yl]Pyridine is a high-value, heterocyclic organic compound featuring a pyridine core linked to a substituted pyrazole ring, serving as a critical building block in advanced chemical synthesis. This compound is essential for research and development in the pharmaceutical sector, where it is utilized as a key intermediate for creating novel active pharmaceutical ingredients (APIs) and drug candidates. Its unique structure makes it particularly valuable for medicinal chemists and R&D laboratories focused on developing new therapeutic agents, especially in areas requiring fluorinated aromatic systems.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization studies to explore structure-activity relationships (SAR) due to its fluorobenzyl and pyrazole motifs.
• Agrochemical Development: Serves as a building block for creating new crop protection agents and pesticides, leveraging its heterocyclic framework.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a potential monomer or ligand for creating specialty polymers and metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up development.

Basic Information

Product Name	4-[5-(4-Fluorobenzyl)-1H-Pyrazol-3-Yl]Pyridine
CAS No.	1001112-68-0
Molecular Formula	C15H12FN3
Molecular Weight	253.28 g/mol
Synonyms	4-[5-(4-Fluorophenylmethyl)-1H-pyrazol-3-yl]pyridine; 3-Pyridin-4-yl-5-(4-fluorobenzyl)-1H-pyrazole; 5-(4-Fluorobenzyl)-3-(4-pyridyl)-1H-pyrazole; 4-(5-((4-Fluorophenyl)methyl)-1H-pyrazol-3-yl)pyridine; 1H-Pyrazole, 5-[(4-fluorophenyl)methyl]-3-(4-pyridinyl)-; 1001112-68-0; 4-(5-(4-Fluorobenzyl)-1H-pyrazol-3-yl)pyridine
EINECS	Contact for details

Quality Control

Our 4-[5-(4-Fluorobenzyl)-1H-Pyrazol-3-Yl]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports research and development requiring high-purity building blocks for reliable and reproducible results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.