Description

1-Benzenesulfonyl-5-Bromo-1H-Pyrrolo[2,3-B]Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its fused pyrrolopyridine core functionalized with bromine and a benzenesulfonyl protecting group. This compound is of critical importance for medicinal chemistry research and development, serving as a versatile and key building block in the synthesis of complex bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology industries for creating novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its modifiable bromine and sulfonyl groups.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and further functionalization to create diverse chemical libraries.
• Material Science Research: Potential precursor for the synthesis of organic electronic materials due to its conjugated heterocyclic system.

Basic Information

Product Name	1-Benzenesulfonyl-5-Bromo-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1001070-33-2
Molecular Formula	C13H9BrN2O2S
Molecular Weight	337.19 g/mol
Synonyms	5-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1H-pyrrolo[2,3-b]pyridine 1-benzenesulfonate; 1-(Phenylsulfonyl)-5-bromo-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-Benzenesulfonyl-5-bromo-7-azaindole; 5-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine (common name); 1001070-33-2
EINECS	Contact for details

Quality Control

Our 1-Benzenesulfonyl-5-Bromo-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.