Description

Ethyl 6,8-Difluoroh-Imidazo[1,2-A]Pyridine-2-Carboxylate is a high-purity fluorinated heterocyclic building block of significant importance in modern pharmaceutical and agrochemical research. This compound serves as a critical synthetic intermediate for the development of novel active ingredients, enabling the introduction of the imidazopyridine scaffold with strategic fluorine substitution. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to enhance molecular properties such as bioavailability, metabolic stability, and binding affinity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the difluoro-imidazopyridine moiety contributes to efficacy and environmental profile.
• Chemical Biology & Probe Development: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways and enzyme functions.
• Material Science: Potential building block for advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) or semiconductors, due to its fused heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development projects for global clients.
• Academic Research: Utilized in university and institutional laboratories for methodological studies in fluorination chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	Ethyl 6,8-Difluoroh-Imidazo[1,2-A]Pyridine-2-Carboxylate
CAS No.	1000844-18-7
Molecular Formula	C10H8F2N2O2
Molecular Weight	226.18 g/mol
Synonyms	Ethyl 6,8-Difluoroimidazo[1,2-a]pyridine-2-carboxylate; 6,8-Difluoroimidazo[1,2-a]pyridine-2-carboxylic Acid Ethyl Ester; Imidazo[1,2-a]pyridine-2-carboxylic acid, 6,8-difluoro-, ethyl ester; 1000844-18-7; Ethyl 6,8-difluoroimidazo[1,2-a]pyridine-2-carboxylate; 2-Carbethoxy-6,8-difluoroimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our Ethyl 6,8-Difluoroh-Imidazo[1,2-A]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and Mass Spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.