Description

2-(6-Bromo-2H-Benzo[B][1,4]Oxazin-4(3H)-Yl)-6,6-Dimethyl-6,7-Dihydrothiazolo[5,4-C]Pyridin-4(5H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, process R&D, and the production of targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis to discover new bioactive molecules.
• Process Development & Scale-up: Employed in optimizing synthetic routes from laboratory to pilot and commercial scale production under cGMP guidelines.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for the production of clinical trial materials and commercial APIs.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or conjugates for biochemical and diagnostic applications due to its reactive bromo group.

Basic Information

Product Name	2-(6-Bromo-2H-Benzo[B][1,4]Oxazin-4(3H)-Yl)-6,6-Dimethyl-6,7-Dihydrothiazolo[5,4-C]Pyridin-4(5H)-One
CAS No.	1000793-42-9
Molecular Formula	C17H15BrN4O2S
Molecular Weight	419.30 g/mol
Synonyms	6-Bromo-4-(4,5-dihydro-6,6-dimethyl-4-oxothiazolo[5,4-c]pyridin-2(3H)-yl)-2H-1,4-benzoxazin-3(4H)-one; 2-(6-Bromo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)-6,6-dimethyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-4-one; 1000793-42-9; Benzoxazine-thiazolopyridinone derivative; Bromo-benzoxazinyl-dihydrothiazolopyridinone
EINECS	Contact for details

Quality Control

Every batch of 2-(6-Bromo-2H-Benzo[B][1,4]Oxazin-4(3H)-Yl)-6,6-Dimethyl-6,7-Dihydrothiazolo[5,4-C]Pyridin-4(5H)-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the stringent requirements for pharmaceutical R&D and cGMP intermediate production. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.