Description

5-((6-Chloropyridazin-3-Yl)Methyl)-2-(2-Fluorophenyl)-5H-Imidazo[4,5-C]Pyridine is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1000787-76-7. This heterocyclic compound is of significant value in medicinal chemistry research and development, particularly for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, especially within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: The imidazopyridine-pyridazine hybrid structure is valuable for designing potential kinase inhibitors, a major class of targeted cancer therapies.
• CNS Drug Discovery: Employed in the research of new compounds for neurological and psychiatric disorders due to the pharmacophore's potential blood-brain barrier permeability.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-((6-Chloropyridazin-3-Yl)Methyl)-2-(2-Fluorophenyl)-5H-Imidazo[4,5-C]Pyridine
CAS No.	1000787-76-7
Molecular Formula	C₁₇H₁₁ClFN₅
Molecular Weight	339.75 g/mol
Synonyms	2-(2-Fluorophenyl)-5-[(6-chloropyridazin-3-yl)methyl]-5H-imidazo[4,5-c]pyridine; 5-((6-Chloro-3-pyridazinyl)methyl)-2-(2-fluorophenyl)-5H-imidazo[4,5-c]pyridine; 5-[(6-Chloropyridazin-3-yl)methyl]-2-(2-fluorophenyl)imidazo[4,5-c]pyridine; 1000787-76-7; UNII-7V8T2F9W4F; 7V8T2F9W4F; AKOS025310947; ZINC000257630607
EINECS	Contact for details

Quality Control

Our production of 5-((6-Chloropyridazin-3-Yl)Methyl)-2-(2-Fluorophenyl)-5H-Imidazo[4,5-C]Pyridine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for purity, related substances, and residual solvents. Our quality system is designed to support regulatory filings and ensure supply chain reliability for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.