Description

n-Boc-3-Dimethylaminopiperidine is a protected piperidine derivative that serves as a crucial chiral building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive nitrogen-containing scaffold, enabling the efficient construction of complex molecular architectures. Pharmaceutical and agrochemical research organizations need it for developing active pharmaceutical ingredients (APIs), novel drug candidates, and other fine chemicals where precise stereochemistry and functional group manipulation are paramount.

Application

• Pharmaceutical Intermediate: Key synthon for the development of central nervous system (CNS) drugs, kinase inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with specific chiral activity.
• Ligand and Catalyst Development: Precursor for synthesizing chiral ligands used in asymmetric catalysis.
• Peptidomimetic Research: Used to introduce constrained piperidine motifs into peptide backbones to enhance stability and bioavailability.
• Chemical Biology Probes: Utilized in the synthesis of tool compounds for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	n-Boc-3-Dimethylaminopiperidine
CAS No.	1000576-83-9
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	tert-Butyl 3-(dimethylamino)piperidine-1-carboxylate; 1-Boc-3-(N,N-dimethylamino)piperidine; 3-(Dimethylamino)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-3-(dimethylamino)piperidine; 3-Dimethylaminopiperidine-1-carboxylic acid tert-butyl ester; N-Boc-3-(dimethylamino)piperidine; 3-(N,N-Dimethylamino)piperidine-1-Boc
EINECS	Contact for details

Quality Control

Our n-Boc-3-Dimethylaminopiperidine is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and development, with typical purity levels exceeding 97% (by HPLC). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Specifications can be tailored to meet specific project requirements, including cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.