Description

6-Benzyl-3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine is a high-value, heterocyclic organic compound featuring a brominated naphthyridine core with a benzyl substituent. This advanced pharmaceutical intermediate is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns for structure-activity relationship (SAR) studies due to its modifiable bromine and benzyl groups.
• Ligand and Catalyst Development: Acts as a precursor or scaffold for creating novel ligands in asymmetric catalysis or metal-organic frameworks (MOFs).
• Agrochemical Synthesis: Employed in the research and development of new generation herbicides, fungicides, or plant growth regulators.
• Academic Research: A valuable compound for university and institutional research in organic synthesis methodologies and heterocyclic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	6-Benzyl-3-Bromo-5,6,7,8-Tetrahydro-1,6-Naphthyridine
CAS No.	1000576-67-9
Molecular Formula	C₁₅H₁₅BrN₂
Molecular Weight	303.20 g/mol
Synonyms	3-Bromo-6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine; 6-Benzyl-3-bromo-5,6,7,8-tetrahydro[1,6]naphthyridine; 1,6-Naphthyridine, 3-bromo-5,6,7,8-tetrahydro-6-(phenylmethyl)-; 3-Bromo-6-benzyl-5,6,7,8-tetrahydro-1,6-naphthyridine; Tetrahydro-1,6-naphthyridine derivative
EINECS	Contact for details

Quality Control

Our 6-Benzyl-3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.