Description

2-(5-Fluoro-Pyridin-3-Yl)-Ethylamine is a high-purity fluorinated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its core value lies in providing a functionalized amine handle attached to a fluorinated heterocyclic core, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Bioconjugation and Probe Synthesis: The primary amine group is ideal for creating fluorescent probes, biomarkers, and antibody-drug conjugates (ADCs) for diagnostic and therapeutic applications.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring fluorinated pyridine motifs.

Basic Information

Product Name	2-(5-Fluoro-Pyridin-3-Yl)-Ethylamine
CAS No.	1000537-08-5
Molecular Formula	C7H9FN2
Molecular Weight	140.16 g/mol
Synonyms	3-(2-Aminoethyl)-5-fluoropyridine; 5-Fluoro-3-(2-aminoethyl)pyridine; 2-(5-Fluoropyridin-3-yl)ethan-1-amine; 5-Fluoro-3-pyridineethanamine; 3-(2-Aminoethyl)-5-fluoropyridine; 1000537-08-5; 2-(5-Fluoro-3-pyridyl)ethylamine
EINECS	Contact for details

Quality Control

Every batch of 2-(5-Fluoro-Pyridin-3-Yl)-Ethylamine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA), including results from HPLC, GC, NMR, and MS, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.