Description

3-Chloro-5-(Trifluoromethyl)Pyridine-2-Acetic Acid is a high-value, multifunctional pyridine derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, combining a halogenated pyridine core with a reactive acetic acid side chain, makes it indispensable for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drugs targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl and chloro groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the development of novel organic electronic materials, such as electron-transport layers or components for organic light-emitting diodes (OLEDs).
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Chloro-5-(Trifluoromethyl)Pyridine-2-Acetic Acid
CAS No.	1000522-34-8
Molecular Formula	C8H5ClF3NO2
Molecular Weight	239.58 g/mol
Synonyms	2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)acetic acid; [3-Chloro-5-(trifluoromethyl)-2-pyridyl]acetic acid; 3-Chloro-5-trifluoromethylpicolinic acid derivative; 2-Pyridineacetic acid, 3-chloro-5-(trifluoromethyl)-; 3-Chloro-5-(trifluoromethyl)-2-pyridineacetic acid; 1000522-34-8 (CAS); 3-Chloro-5-(trifluoromethyl)picolinic acid acetic acid derivative
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-(Trifluoromethyl)Pyridine-2-Acetic Acid is manufactured and tested under a strict quality management system to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as confirmed by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from incompatible materials such as strong bases and oxidizing agents. The container must be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.