Description

(E)-3-(2,6-Dichloropyridin-3-Yl)Acrylamide is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functionalized pyridine-acrylamide structure. This compound is of significant value for its role as a versatile building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated pyridine moiety for bioactivity.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme function and protein interactions.
• Material Science: Potential monomer or cross-linking agent for creating specialized polymers with unique thermal or optical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	(E)-3-(2,6-Dichloropyridin-3-Yl)Acrylamide
CAS No.	1000519-96-9
Molecular Formula	C8H6Cl2N2O
Molecular Weight	217.05 g/mol
Synonyms	(E)-3-(2,6-Dichloro-3-pyridinyl)-2-propenamide; 2-Propenamide, 3-(2,6-dichloro-3-pyridinyl)-, (2E)-; 3-(2,6-Dichloropyridin-3-yl)acrylamide; (E)-3-(2,6-Dichloro-3-pyridyl)acrylamide; (E)-3-(2,6-Dichloro-3-pyridinyl)acrylamide; (E)-3-(2,6-Dichloropyridin-3-yl)prop-2-enamide
EINECS	Contact for details

Quality Control

Our (E)-3-(2,6-Dichloropyridin-3-Yl)Acrylamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.