Description

5-Bromo-3-Iodo-6-Methyl-7-Azaindole is a high-value, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both bromine and iodine atoms on an azaindole scaffold, makes it a versatile precursor for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients. Its role is critical in medicinal chemistry programs targeting novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and oncology research programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Precursor: Acts as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: The bromine and iodine substituents are excellent handles for Suzuki, Sonogashira, and Buchwald-Hartwig amination reactions to create diverse chemical libraries.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	5-Bromo-3-Iodo-6-Methyl-7-Azaindole
CAS No.	1000343-82-7
Molecular Formula	C8H6BrIN2
Molecular Weight	352.96 g/mol
Synonyms	5-Bromo-3-iodo-6-methyl-1H-pyrrolo[2,3-b]pyridine; 6-Methyl-5-bromo-3-iodo-7-azaindole; 3-Iodo-5-bromo-6-methyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-3-iodo-6-methyl-; 5-Bromo-3-iodo-6-methyl-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-Iodo-6-Methyl-7-Azaindole is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (HPLC), identity (NMR, IR), and impurity profile. Our quality control protocols are designed to support regulatory filings and ensure batch-to-batch consistency for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.