Description

3-Bromo-5-Azaindole-4-Carboxylic Acid is a high-value heterocyclic building block, specifically a functionalized azaindole derivative. This compound is essential for medicinal chemistry research and development, serving as a key precursor for synthesizing novel small molecule inhibitors and targeted therapies. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing kinase inhibitors and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Research: Serves as a precursor for developing chemical probes to study specific enzyme functions and signaling pathways.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex heterocyclic molecules for advanced material and agrochemical applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical candidates.

Basic Information

Product Name	3-Bromo-5-Azaindole-4-Carboxylic Acid
CAS No.	1000341-43-4
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	4-Carboxy-3-bromo-7-azaindole; 3-Bromo-1H-pyrrolo[2,3-b]pyridine-4-carboxylic acid; 3-Bromo-7-azaindole-4-carboxylic acid; 1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid, 3-bromo-; 3-Bromo-4-carboxy-7-azaindole; 3-Bromo-4-carboxy-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Azaindole-4-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, supporting our commitment to reliable supply and technical data integrity for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under an inert atmosphere if necessary and opened in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.