Description

1-Acetyl-4-Bromo-7-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated azaindole structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of protein kinase inhibitors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex molecular fragments.
• Biochemical Tool Compound: Employed in the study of enzymatic pathways and cellular signaling mechanisms.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.

Basic Information

Product Name	1-Acetyl-4-Bromo-7-Azaindole
CAS No.	1000340-84-0
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	4-Bromo-1-acetyl-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-1-acetyl-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-1-acetyl-; 4-Bromo-1-(acetyl)-7-azaindole; 1-Acetyl-4-bromo-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1-Acetyl-4-Bromo-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.