Description

1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 6-Chloro- is a high-value, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a critical intermediate in the development of novel pharmaceuticals and agrochemicals, where its fused pyrrolopyridine core provides a versatile scaffold for drug discovery. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the synthesis of kinase inhibitors and other biologically active molecules. Our supply ensures high purity and batch-to-batch consistency for reliable research and scale-up processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Chemical Biology: Serves as a versatile scaffold for constructing molecular probes and libraries in high-throughput screening.
• Material Science: Potential building block for advanced organic electronic materials due to its electron-deficient π-conjugated system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 6-Chloro-
CAS No.	1000340-76-0
Molecular Formula	C8H4ClN3
Molecular Weight	177.59 g/mol
Synonyms	6-Chloro-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile; 6-Chloro-4-cyano-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile; 4-Cyano-6-chloro-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile, 6-chloro-; 6-Chloro-4-cyanopyrrolo[2,3-b]pyridine; 6-Chloro-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS 1000340-76-0)
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 6-Chloro- is manufactured under a strict quality management system. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We support cGMP compliance for advanced applications and can tailor specifications to meet your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.