Description

1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 6-Bromo- is a high-purity heterocyclic building block of significant importance in modern organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators with novel modes of action.
• Material Science: Building block for creating organic semiconductors, light-emitting diodes (OLEDs), and other electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Custom Synthesis: Serves as a versatile starting material for contract research organizations (CROs) and CDMOs for client-specific projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 6-Bromo-
CAS No.	1000340-74-8
Molecular Formula	C8H4BrN3
Molecular Weight	222.04 g/mol
Synonyms	6-Bromo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile; 6-Bromo-4-cyano-1H-pyrrolo[2,3-b]pyridine; 6-Bromo-4-cyanopyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile, 6-bromo-; 6-Bromo-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile; 4-Cyano-6-bromo-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 6-Bromo- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient humidity. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.