Description

1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 3-Amino- is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. Its core value lies in its bifunctional molecular scaffold, featuring both an amino group and a nitrile moiety, which enables its use as a versatile precursor for constructing complex pharmacophores. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, particularly those targeting kinase inhibition.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of kinase inhibitor drugs for oncology and inflammatory diseases.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides and fungicides with specific modes of action.
• Material Science Research: Serves as a precursor for the synthesis of organic semiconductors and functional dyes due to its electron-deficient pyrrolopyridine core.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 3-Amino-
CAS No.	1000340-50-0
Molecular Formula	C8H6N4
Molecular Weight	158.16 g/mol
Synonyms	3-Amino-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile; 3-Amino-4-cyano-1H-pyrrolo[2,3-b]pyridine; 4-Cyano-1H-pyrrolo[2,3-b]pyridin-3-amine; 1H-Pyrrolo[2,3-b]pyridine-4-carbonitrile, 3-amino-; 3-Amino-4-cyanopyrrolo[2,3-b]pyridine; 3-Amino-1H-7-azaindole-4-carbonitrile; 7-Azaindole-4-carbonitrile, 3-amino-
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-4-Carbonitrile, 3-Amino- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and pre-clinical development. Certificates of Analysis (COA) with full analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.