Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 4-Nitro- is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitor candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery and lead optimization programs.
• Agrochemical Development: Used in research for creating new agrochemicals, leveraging its heterocyclic core for potential herbicidal or pesticidal activity.
• Material Science: Investigated as a monomer or precursor for specialty polymers and organic electronic materials due to its conjugated system.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme function and cellular signaling pathways.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 4-Nitro-
CAS No.	1000340-44-2
Molecular Formula	C9H5N3O4
Molecular Weight	219.16 g/mol
Synonyms	4-Nitro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 4-Nitro-7-azaindole-3-carboxylic acid; 4-Nitro-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 4-Nitro-7-azaindole-3-carboxylic acid; 4-Nitropyrrolo[2,3-b]pyridine-3-carboxylic acid; 3-Carboxy-4-nitro-7-azaindole; 4-Nitro-1H-pyrrolo[2,3-b]pyridin-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 4-Nitro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.