Description

tert-Butyl 4-Hydroxypent-2-Ynoate (Wxc07449) is a high-purity, specialized chemical building block featuring a terminal alkyne and a protected hydroxyl group. This compound is valued for its versatility in advanced organic synthesis, particularly in click chemistry and the construction of complex molecular architectures. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs) via Huisgen cycloaddition (click chemistry) and other coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators requiring specific alkyne functionalities.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored properties, such as conductive materials or hydrogels.
• Bioconjugation & Probe Synthesis: Enables the labeling of biomolecules (proteins, peptides, nucleic acids) for diagnostic assays and imaging applications.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to construct complex natural products and novel heterocyclic compounds.
• Ligand & Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in catalytic systems for asymmetric synthesis.

Basic Information

Product Name	tert-Butyl 4-Hydroxypent-2-Ynoate (Wxc07449)
CAS No.	1000021-62-4
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	4-Hydroxypent-2-ynoic acid tert-butyl ester; tert-Butyl 4-hydroxypent-2-ynoate; 2-Butynoic acid, 4-hydroxy-, 1,1-dimethylethyl ester; WXC07449; tert-Butyl 4-hydroxypent-2-ynoate; 4-Hydroxy-2-pentynoic acid tert-butyl ester; 1,1-Dimethylethyl 4-hydroxy-2-pentynoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Hydroxypent-2-Ynoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.