Description

8-Bromo-6-Chloroimidazo[1,2-A]Pyridine-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical precursor for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical R&D teams and fine chemical manufacturers need this specialized intermediate for creating next-generation therapeutic agents, leveraging its unique halogenated imidazopyridine core to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology, antiviral, and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the halogenated heterocycle contributes to bioactivity and environmental stability.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes and inhibitors for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity intermediates.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-6-Chloroimidazo[1,2-A]Pyridine-2-Carboxylic Acid
CAS No.	1000017-98-0
Molecular Formula	C8H4BrClN2O2
Molecular Weight	275.49 g/mol
Synonyms	8-Bromo-6-chloro-2-imidazo[1,2-a]pyridinecarboxylic acid; 6-Chloro-8-bromoimidazo[1,2-a]pyridine-2-carboxylic acid; Imidazo[1,2-a]pyridine-2-carboxylic acid, 8-bromo-6-chloro-; 1000017-98-0; 8-Br-6-Cl-Imidazo[1,2-a]pyridine-2-COOH
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Chloroimidazo[1,2-A]Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.