Description

3-Chloroimidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in serving as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas targeting the central nervous system, inflammation, and oncology.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and pesticides, leveraging its fused heterocyclic structure.
• Chemical Biology & Probe Development: Serves as a scaffold for creating fluorescent probes, enzyme inhibitors, and other tools for biological research.
• Material Science Precursor: Potential building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies and the exploration of new chemical reactions.
• Custom Synthesis & Scale-Up: A critical starting material for custom manufacturing organizations (CMOs) engaged in process optimization and pilot-scale production for clients.

Basic Information

Product Name	3-Chloroimidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	1000017-95-7
Molecular Formula	C10H9ClN2O2
Molecular Weight	224.64 g/mol
Synonyms	Ethyl 3-Chloroimidazo[1,2-a]pyridine-2-carboxylate; 3-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester; Imidazo[1,2-a]pyridine-2-carboxylic acid, 3-chloro-, ethyl ester; 3-Chloro-2-ethoxycarbonylimidazo[1,2-a]pyridine; Ethyl 3-chloro-2-imidazo[1,2-a]pyridinecarboxylate; 3-Chloroimidazo(1,2-a)pyridine-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 3-Chloroimidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.