Description

Acetic Acid 3-Chloro-4-Fluoro-Phenyl Ester is a specialized fluorinated aromatic ester building block. This high-purity intermediate is critical for the synthesis of advanced pharmaceutical compounds and agrochemicals, offering precise reactivity for introducing the 3-chloro-4-fluorophenyl moiety. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking reliable, high-quality synthetic intermediates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the chloro-fluoro substitution pattern enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce aromatic ester functionalities into polymer chains, modifying thermal and solubility properties.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in academic and industrial laboratories.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	Acetic Acid 3-Chloro-4-Fluoro-Phenyl Ester
CAS No.	199586-28-2
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	3-Chloro-4-fluorophenyl acetate; 1-Acetoxy-3-chloro-4-fluorobenzene; (3-Chloro-4-fluorophenyl) ethanoate; Acetic acid (3-chloro-4-fluoro)phenyl ester; 3-Chloro-4-fluoro phenol acetate; 4-Fluoro-3-chlorophenyl acetate; p-Fluoro-m-chlorophenyl acetate; CAS 199586-28-2
EINECS	Contact for details

Quality Control

Our Acetic Acid 3-Chloro-4-Fluoro-Phenyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment. We adhere to cGMP guidelines where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption and potential decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.30 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.