Description

Propanedioic Acid, (4-Bromo-2-Nitrophenyl)-, Diethyl Ester is a specialized organic intermediate featuring a bromo-nitrophenyl functional group attached to a diethyl malonate core. This compound matters for its role as a versatile building block in the synthesis of complex heterocyclic and pharmaceutical compounds, enabling the introduction of key functional handles for further chemical elaboration. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex aromatic and heterocyclic structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive bromo and nitro groups.
• Organic Synthesis Building Block: Serves as a versatile starting material for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions.
• Dye and Pigment Research: Employed in the development of specialized dyes and organic pigments due to its nitrophenyl chromophore.
• Material Science Research: Investigated as a monomer or functional additive in the creation of advanced polymers with specific optical or electronic properties.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies and compound libraries.

Basic Information

Item	Detail
Product Name	Propanedioic Acid, (4-Bromo-2-Nitrophenyl)-, Diethyl Ester
CAS No.	199328-34-2
Molecular Formula	C₁₃H₁₄BrNO₆
Molecular Weight	360.16 g/mol
Synonyms	Diethyl (4-Bromo-2-nitrophenyl)malonate; (4-Bromo-2-nitrophenyl)malonic Acid Diethyl Ester; Diethyl 4-Bromo-2-nitrobenzylmalonate; Propanedioic acid, 2-(4-bromo-2-nitrophenyl)-, 1,3-diethyl ester; Malonic acid, (4-bromo-2-nitrophenyl)-, diethyl ester; 1,3-Diethyl 2-(4-bromo-2-nitrophenyl)propanedioate
EINECS	Contact for details

Quality Control

Our Propanedioic Acid, (4-Bromo-2-Nitrophenyl)-, Diethyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), related substances, and physical characteristics are provided and available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.