Description

(S)-2-[4-(1,1-Dimethylethyl)-4,5-Dihydro-2-Oxazolyl]-6-Methylpyridine is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex molecules with specific stereochemistry, which is critical for efficacy in many applications. This compound is essential for research and development laboratories, as well as production facilities, in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry is required for optimal biological activity.
• Ligand for Asymmetric Catalysis: Functions as a component in chiral ligand libraries for metal-catalyzed asymmetric reactions, enabling the production of enantiomerically pure compounds.
• Chemical Research & Development: A valuable tool for academic and industrial chemists exploring new synthetic methodologies and constructing complex molecular architectures.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, specialized fine chemicals and advanced materials.

Basic Information

Product Name	(S)-2-[4-(1,1-Dimethylethyl)-4,5-Dihydro-2-Oxazolyl]-6-Methylpyridine
CAS No.	199277-80-0
Molecular Formula	C14H20N2O
Molecular Weight	232.32 g/mol
Synonyms	(S)-2-(4-tert-Butyl-4,5-dihydrooxazol-2-yl)-6-methylpyridine; (S)-2-(4-tert-Butyl-2-oxazolin-2-yl)-6-picoline; (S)-6-Methyl-2-(4-tert-butyl-4,5-dihydro-2-oxazolyl)pyridine; (S)-2-(4-(tert-Butyl)-4,5-dihydrooxazol-2-yl)-6-methylpyridine; (S)-TB-DHOP; (S)-Pyridine, 2-[4-(1,1-dimethylethyl)-4,5-dihydro-2-oxazolyl]-6-methyl-; (S)-enantiomer of oxazoline-pyridine ligand precursor
EINECS	Contact for details

Quality Control

Our (S)-2-[4-(1,1-Dimethylethyl)-4,5-Dihydro-2-Oxazolyl]-6-Methylpyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity compliant with research and production standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.