Description

Pyridine, 2-[(4R)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-6-Methyl- is a chiral, heterocyclic organic compound featuring a pyridine core fused with a substituted oxazoline ring. This specific stereochemistry and molecular architecture make it a valuable advanced pharmaceutical intermediate (API) and a versatile chiral building block for asymmetric synthesis. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the creation of novel, optically active compounds, including potential drug candidates and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or requiring specific stereochemistry.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands used in metal-catalyzed asymmetric reactions to create enantiomerically pure compounds.
• Agrochemical Research: Used in the development of new, more selective herbicides, fungicides, or insecticides where the specific stereochemistry can influence biological activity.
• Material Science Research: Investigated as a monomer or functional component in the synthesis of specialized polymers and advanced organic materials.
• Academic & Industrial R&D: Employed in chemical research laboratories for methodological studies in organic synthesis and the exploration of new reaction pathways.

Basic Information

Item	Details
Product Name	Pyridine, 2-[(4R)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-6-Methyl-
CAS No.	199277-73-1
Molecular Formula	C15H14N2O
Molecular Weight	238.29 g/mol
Synonyms	(R)-2-(6-Methylpyridin-2-yl)-4,5-dihydro-4-phenyloxazole; (4R)-2-(6-Methyl-2-pyridinyl)-4,5-dihydro-4-phenyloxazole; (R)-2-(6-Methyl-2-pyridyl)-4-phenyl-4,5-dihydrooxazole; 2-[(4R)-4,5-Dihydro-4-phenyl-2-oxazolyl]-6-methylpyridine; (R)-6-Methyl-2-(4-phenyl-4,5-dihydrooxazol-2-yl)pyridine; Chiral Oxazoline-Pyridine Ligand Precursor; (R)-PHOX-type Intermediate
EINECS	Contact for details

Quality Control

Our production of Pyridine, 2-[(4R)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-6-Methyl- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC/SFC), to ensure high enantiomeric excess (ee) and chemical purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, assay, impurity profile, and other critical parameters to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/SFC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.