Description

Pyridine, 2-[(4S)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]-6-Methyl- is a high-purity, chiral oxazoline-substituted pyridine derivative, serving as a sophisticated building block and ligand in advanced chemical synthesis. Its precise stereochemistry and functional groups make it a critical intermediate for the development of pharmaceuticals and fine chemicals requiring high enantiomeric purity. This compound is primarily utilized by research institutions, pharmaceutical R&D departments, and specialty chemical manufacturers engaged in asymmetric catalysis and novel active ingredient development.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Asymmetric Catalysis Ligand: Used as a ligand in transition metal catalysis to induce chirality in C-C and C-N bond-forming reactions, enabling the production of single-enantiomer compounds.
• Agrochemical Research: Employed in the development of novel, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Serves as a functional monomer or additive in the synthesis of advanced polymers and liquid crystals with specific optical properties.
• Academic & Process Chemistry: A valuable tool for methodological development in organic synthesis and scale-up process optimization within R&D laboratories.

Basic Information

Item	Details
Product Name	Pyridine, 2-[(4S)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]-6-Methyl-
CAS No.	199277-70-8
Molecular Formula	C12H16N2O
Molecular Weight	204.27 g/mol
Synonyms	(4S)-4-Isopropyl-2-(6-methylpyridin-2-yl)-4,5-dihydrooxazole; 2-[(4S)-4-Isopropyl-4,5-dihydro-1,3-oxazol-2-yl]-6-methylpyridine; (S)-4-Isopropyl-2-(6-methyl-2-pyridyl)-2-oxazoline; (S)-2-(4-Isopropyl-4,5-dihydrooxazol-2-yl)-6-methylpyridine; (S)-2-(6-Methyl-2-pyridyl)-4-isopropyl-2-oxazoline; Chiral Pyridine-Oxazoline Ligand; (S)-iPr-PyOx; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of our Pyridine, 2-[(4S)-4,5-Dihydro-4-(1-Methylethyl)-2-Oxazolyl]-6-Methyl- is manufactured under strict quality management systems. We guarantee high chiral purity and chemical consistency through advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.