Description

1-((Benzyloxy)Carbonyl)Piperidin-4-Yl Methanesulfonate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern organic synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and process development. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, especially those containing the piperidine scaffold.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a standardized reagent for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Protease Inhibitor Synthesis: A potential precursor in the synthesis of inhibitors targeting various enzymatic pathways.
• Chemical Biology Tool Development: Can be utilized to create functionalized probes for studying biological systems and target engagement.
• Custom Synthesis Projects: Employed by CDMOs for the contract manufacturing of bespoke molecules for client-specific drug discovery programs.

Basic Information

Product Name	1-((Benzyloxy)Carbonyl)Piperidin-4-Yl Methanesulfonate
CAS No.	199103-19-0
Molecular Formula	C15H21NO5S
Molecular Weight	327.40 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-4-piperidinyl methanesulfonate; 1-CBZ-4-Hydroxypiperidine Methanesulfonate; 1-N-CBZ-4-Hydroxypiperidine Mesylate; 4-Hydroxy-1-(phenylmethoxy)carbonylpiperidine Methanesulfonate; 1-(Benzyloxycarbonyl)-4-piperidinol Methanesulfonate; 4-(Methanesulfonyloxy)-1-[(phenylmethoxy)carbonyl]piperidine; Piperidine, 1-[(phenylmethoxy)carbonyl]-4-(methylsulfonyloxy)-
EINECS	Contact for details

Quality Control

Our 1-((Benzyloxy)Carbonyl)Piperidin-4-Yl Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.