Description

D-Alanine, n-(2-Methylpropyl)-, Methyl Ester (9Ci) is a chiral, non-natural amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a high-purity building block for constructing complex molecules with precise stereochemistry, which is critical for developing bioactive compounds. It is needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry, peptide mimetics, and as a chiral auxiliary or intermediate.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other targeted therapies.
• Peptidomimetics Research: Used to create and study peptide analogs with enhanced metabolic stability and bioavailability for drug discovery programs.
• Agrochemical Synthesis: Employed in the development of chiral pesticides and herbicides where specific stereochemistry influences biological activity.
• Chiral Catalyst or Ligand Preparation: Acts as a precursor for synthesizing novel ligands used in asymmetric catalysis.
• Specialty Polymer Modification: Incorporated into polymers to impart specific chiral or functional properties for advanced material science applications.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	D-Alanine, n-(2-Methylpropyl)-, Methyl Ester (9Ci)
CAS No.	198630-68-1
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	D-2-Amino-N-isobutylpropionic acid methyl ester; Methyl (2R)-2-amino-2-methyl-4-(methylsulfanyl)butanoate (related structure); D-Alanine, N-(2-methylpropyl)-, methyl ester; (R)-2-((2-Methylpropyl)amino)propanoic acid methyl ester; D-N-Isobutylalanine methyl ester; Methyl D-2-(isobutylamino)propanoate; (R)-Methyl 2-(isobutylamino)propanoate; L- Alanine, N-(2-methylpropyl)-, methyl ester (enantiomer)
EINECS	Contact for details

Quality Control

Our D-Alanine, n-(2-Methylpropyl)-, Methyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.