Description

Proellex CAS NO 198414-31-2 is a high-purity, non-peptide small molecule compound with significant pharmacological activity. This compound is a selective progesterone receptor modulator (SPRM), making it a critical intermediate and active pharmaceutical ingredient (API) for advanced therapeutic research and development. It is primarily utilized by pharmaceutical companies, biotechnology research institutions, and contract development and manufacturing organizations (CDMOs) engaged in women's health, oncology, and endocrinology.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of final drug substances targeting progesterone receptors.
• Active Pharmaceutical Ingredient (API): Used in the formulation of clinical trial materials and finished dosage forms for therapeutic applications.
• Research & Development: Essential for preclinical and clinical studies investigating treatments for uterine fibroids, endometriosis, and other hormone-dependent conditions.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and analytical method development within pharmaceutical laboratories.
• Biochemical Research: Used in vitro and in vivo studies to understand progesterone receptor signaling pathways and mechanisms of action.

Basic Information

Product Name	Proellex
CAS No.	198414-31-2
Molecular Formula	C30H33NO4
Molecular Weight	471.59 g/mol
Synonyms	Telapristone; CDB-4124; Proellex (Telapristone); 17α-Acetoxy-11β-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione; 11β-[4-(Dimethylamino)phenyl]-17α-hydroxy-19-norpregna-4,9-diene-3,20-dione 17-acetate
EINECS	Contact for details

Quality Control

Our Proellex is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and LC-MS, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) are provided with every shipment to guarantee traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.