Description

Carbamic Acid, Hydroxypropyl-, 9H-Fluoren-9-Ylmethyl Ester (9Ci) is a specialized carbamate derivative primarily used as a key building block and protecting group reagent in advanced organic synthesis. This compound matters for its role in facilitating complex multi-step reactions, particularly in the synthesis of peptides and other sensitive molecules where selective protection and deprotection are critical. Pharmaceutical researchers, agrochemical developers, and fine chemical manufacturers need this high-purity intermediate to ensure the integrity and yield of their target compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for peptide-based drugs and complex organic molecules.
• Peptide Synthesis: Used as an N-protecting group (Fmoc-derivative) in solid-phase and solution-phase peptide synthesis to control reaction sequences.
• Agrochemical Research: Serves as a precursor or intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, dyes, and advanced materials requiring specific carbamate functionalities.
• Bioconjugation Chemistry: Useful in the field of bioconjugation for modifying biomolecules, creating drug-linker systems for antibody-drug conjugates (ADCs).
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic pathways in research settings.

Basic Information

Product Name	Carbamic Acid, Hydroxypropyl-, 9H-Fluoren-9-Ylmethyl Ester (9Ci)
CAS No.	198411-61-9
Molecular Formula	C19H19NO4
Molecular Weight	325.36 g/mol
Synonyms	N-(9-Fluorenylmethoxycarbonyl)-3-hydroxypropylamine; Fmoc-3-amino-1-propanol; 3-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-1-propanol; N-Fmoc-3-aminopropanol; 3-(Fmoc-amino)-1-propanol; N-(9-Fluorenylmethyloxycarbonyl)-3-aminopropanol; Hydroxypropylcarbamic acid 9H-fluoren-9-ylmethyl ester; Fmoc-NH-(CH2)3-OH
EINECS	Contact for details

Quality Control

Our Carbamic Acid, Hydroxypropyl-, 9H-Fluoren-9-Ylmethyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.