Description

(4-Trifluoromethyl-Pyridin-3-Yl)-Methanol is a high-value fluorinated pyridine derivative, a crucial building block in modern synthetic chemistry. Its unique structure, featuring a trifluoromethyl group and a hydroxymethyl substituent on the pyridine ring, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in areas like kinase inhibitors, antiviral agents, and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) used in asymmetric catalysis.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, or organic electronic materials due to its aromatic and fluorinated characteristics.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	(4-Trifluoromethyl-Pyridin-3-Yl)-Methanol
CAS No.	198401-76-2
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	3-(Hydroxymethyl)-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-3-pyridinemethanol; (4-Trifluoromethyl-3-pyridyl)methanol; 3-Pyridinemethanol, 4-(trifluoromethyl)-; α-(4-Trifluoromethyl-3-pyridyl)methanol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chemical intermediates. Each batch of (4-Trifluoromethyl-Pyridin-3-Yl)-Methanol is analyzed using advanced techniques like HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.