Description

3-o-[(tert-Butyldiphenylsilyl]-6-o-(D,L-1-Ethoxyethyl)-1,2:4,5-Bis-o-(1-Methylethylidene)-D,L-Myo-Inositol CAS NO 197848-72-9 is a sophisticated, multi-protected derivative of myo-inositol, a key building block in carbohydrate and medicinal chemistry. This compound is specifically engineered as a crucial synthetic intermediate, offering selective deprotection pathways for the controlled synthesis of complex inositol phosphates and glycoconjugates. It is primarily utilized by research institutions and pharmaceutical development teams engaged in the synthesis of novel therapeutic agents, signaling molecules, and advanced chemical probes.

Application

• Pharmaceutical Intermediate: A key protected precursor in the multi-step synthesis of phosphatidylinositol (PI) derivatives and inositol phosphate analogs with potential therapeutic activity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing complex glycomimetics and carbohydrate-based drug candidates targeting various biological pathways.
• Chemical Biology Tool Development: Used to create labeled or modified inositol probes for studying intracellular signaling processes, such as those involving phosphoinositides.
• Organic Synthesis Building Block: Provides a strategically protected inositol core for the synthesis of natural products and complex chiral molecules requiring precise stereochemical control.
• Glycoconjugate Synthesis: Enables the controlled attachment of sugar moieties or other functional groups to specific positions on the inositol ring for advanced material or biochemical applications.

Basic Information

Product Name	3-o-[(tert-Butyldiphenylsilyl]-6-o-(D,L-1-Ethoxyethyl)-1,2:4,5-Bis-o-(1-Methylethylidene)-D,L-Myo-Inositol
CAS No.	197848-72-9
Molecular Formula	C34H48O7Si
Molecular Weight	596.83 g/mol
Synonyms	1,2:4,5-Di-O-isopropylidene-3-O-(tert-butyldiphenylsilyl)-6-O-[(1-ethoxy)ethyl]-myo-inositol; 3-O-TBDPS-6-O-EE-1,2:4,5-di-O-isopropylidene-myo-inositol; D,L-1,2:4,5-Di-O-isopropylidene-myo-inositol 3-O-(tert-butyldiphenylsilyl) 6-O-(1-ethoxyethyl) ether; Protected myo-Inositol derivative; TBDPS/EE/Di-isopropylidene myo-inositol
EINECS	Contact for details

Quality Control

This high-value synthetic intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity essential for research and development. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.