Description

(6-[2-(Trifluoromethoxy)Phenyl]Pyridin-3-Yl)Methanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the unique trifluoromethoxy-phenyl-pyridine scaffold, which imparts desirable properties like metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients. Its precise structure makes it a sought-after intermediate for constructing complex molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced efficacy and environmental profile.
• Material Science Research: Acts as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging reagent in the design of chemical probes and enzyme inhibitors for biological pathway studies.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	(6-[2-(Trifluoromethoxy)Phenyl]Pyridin-3-Yl)Methanol
CAS No.	197847-95-3
Molecular Formula	C13H10F3NO2
Molecular Weight	269.22 g/mol
Synonyms	3-Pyridinemethanol, 6-[2-(trifluoromethoxy)phenyl]-; [6-(2-Trifluoromethoxyphenyl)pyridin-3-yl]methanol; 6-(2-(Trifluoromethoxy)phenyl)nicotinyl alcohol; (6-(2-(Trifluoromethoxy)phenyl)pyridin-3-yl)methanol; 2-(Trifluoromethoxy)-6-(hydroxymethyl)pyridine; Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our production of (6-[2-(Trifluoromethoxy)Phenyl]Pyridin-3-Yl)Methanol adheres to stringent internal quality standards, ensuring batch-to-batch consistency for research and development applications. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, for comprehensive identity confirmation and purity verification. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. We support development projects with the capability to tailor specifications to meet specific project requirements, including those for pre-clinical and early-phase clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.